Product Name	ZnT-1
Chinese Name	锌Transporter1抗体
Alias	SLC30 A1; SLC30A 1; SLC30A1; Solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 (zinc transporter), member1; Solute carrier family 30 member 1; Solute carrier family 30, member 1; Zinc transporter 1; Zinc transporter1; ZNT 1; ZnT-1; ZNT1_HUMAN; ZRC 1; ZRC1.
literatures	Specific References  (1)     |     SL6440R has been referenced in 1 publications. [IF=6.543] Xiao Chuanpi. et al. High Temperature-Induced Oxidative Stress Affects Systemic Zinc Homeostasis in Broilers by Regulating Zinc Transporters and Metallothionein in the Liver and Jejunum. Oxid Med Cell Longev. 2022;2022:1427335  WB ;  Broiler Chicks.   PubMed:35387265
Research Area	Cell biology  immunology  Developmental biology  Neurobiology  transcriptional regulatory factor  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	55kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZnT-1: 131-330/507
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein, localizes to the plasma membrane to aid in the export of zinc out of cells. Function: May be involved in zinc transport out of the cell. Subunit: Multimer. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. SWISS: Q9Y6M5 Gene ID: 7779 Database links: Entrez Gene: 7779 Human Entrez Gene: 22782 Mouse Entrez Gene: 58976 Rat Omim: 609521 Human SwissProt: Q9Y6M5 Human SwissProt: Q60738 Mouse SwissProt: Q62720 Rat Unigene: 519469 Human Unigene: 9024 Mouse Unigene: 10120 Rat
Product Picture	Sample:Large intestine (mouse) Lysate at 40 ug Primary: Anti- ZnT-1(SL6440R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55kD Observed band size: 55kD Sample:Lovo cell (human) Lysate at 40 ug Primary: Anti- ZnT-1(SL6440R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55kD Observed band size: 55kD Sample: Lane 1: Mouse Small intestine tissue lysates Lane 2: Mouse Heart tissue lysates Lane 3: Rat Small intestine tissue lysates Lane 4: Rat Heart tissue lysates Lane 5: Human HeLa cell lysates Lane 6: Human U251 cell lysates Lane 7: Human K562 cell lysates Lane 8: Human HepG2 cell lysates Primary: Anti-ZnT-1 (SL6440R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kDa Observed band size: 50 kDa

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