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Product Name Annexin A8 Chinese Name 膜粘连蛋白8抗体 Alias Annexin A8 like2; AnnexinA8; annexin A8L2; ANXA8; ANXA8L2; Annexin VIII; ANXA8_HUMAN. Research Area Cardiovascular Cell biology Signal transduction Cell adhesion molecule Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Cow, Horse, ) Applications WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 37kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Annexin A8: 101-200/327 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Annexin A8 like 2 is a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The protein may function as an anticoagulant that indirectly inhibits the thromboplastin-specific complex, and overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
Function:
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Similarity:
Belongs to the annexin family.
Contains 4 annexin repeats.
SWISS:
P13928
Gene ID:
244
Database links:Entrez Gene: 244 Human
Entrez Gene: 653145 Human
Entrez Gene: 11752 Mouse
Omim: 602396 Human
SwissProt: P13928 Human
SwissProt: O35640 Mouse
Unigene: 535306 Human
Unigene: 705389 Human
Unigene: 3267 Mouse
Unigene: 104326 Rat
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