Product Name	HLC3/Kanadaptin
Chinese Name	肺癌癌基因蛋白3抗体
Alias	HLC3; HLC-3; Human lung cancer oncogene 3 protein; Kanadaptin; Kidney anion exchanger adapter protein; Kidney anion exchanger adaptor protein; Lung cancer oncogene 3 protein; NADAP_HUMAN; SLC4A1AP; Solute carrier family 4 (anion exchanger) member 1 adaptor protein; Solute carrier family 4 anion exchanger member 1 adapter protein.
Research Area	Tumour  Cardiovascular  Cell biology  TumourCell biologyMaker
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	89kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Kanadaptin: 401-500/796
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	HLC-3 is a 796 amino acid protein that is widely expressed in many tissues, including kidney, lung, liver, brain and skeletal and cardiac muscle. SLC4A1AP is a multidomain protein that localizes to the nucleus where it may play a role in signaling. SLC4A1AP was previously thought to act as an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane. However, recent studies suggest SLC4A1AP does not interact with kAE1. The gene encoding SLC4A1AP maps to chromosome 2, which consists of 237 million bases and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Subcellular Location: Nucleus. Cytoplasm. Mainly nuclear. Small amounts are found in the cytoplasm. Tissue Specificity: Ubiquitously expressed. Similarity: Contains 1 FHA domain. SWISS: Q9BWU0 Gene ID: 22950 Database links: Entrez Gene: 22950 Human Entrez Gene: 20534 Mouse Omim: 602655 Human SwissProt: Q9BWU0 Human Unigene: 306000 Human Unigene: 352407 Mouse

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