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Product Name SERPINB4 Chinese Name 丝氨酸蛋白酶抑制剂B4/鳞状细胞癌抗原2抗体 Alias SCCA 2; SCCA2; Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor (leucine serpin); SCCA-2; SCCA1; SCCA2/SCCA1 fusion protein; Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; Serpin B4; Serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2. literatures Specific References (1) | SL6282R has been referenced in 1 publications.[IF=6.057] Limin Zhou. et al. Copper doped terbium metal organic framework as emitter for sensitive electrochemiluminescence detection of CYFRA 21-1. Talanta. 2022 Feb;238:123047Research Area Tumour Cell biology immunology TumourCell biologyMaker Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 45kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SERPINB4: 121-220/390 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May act as a protease inhibitor to modulate the host immune response against tumor cells.
Function:
May act as a protease inhibitor to modulate the host immune response against tumor cells.
Subcellular Location:
Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Tissue Specificity:
Squamous cells.
Similarity:
Belongs to the serpin family. Ov-serpin subfamily.
SWISS:
P48594
Gene ID:
6318
Database links:Entrez Gene: 6318 Human
Omim: 600518 Human
SwissProt: P48594 Human
Unigene: 123035 Human
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