Product Name	FUT8
Chinese Name	岩藻糖转移酶8抗体
Alias	Alpha (1,6) fucosyltransferase; Alpha-(1; Alpha1 6FucT; alpha1-6FucT; Fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Fucosyltransferase 8; FUT8; FUT8_HUMAN; GDP fucose glycoprotein fucosyltransferase; GDP L Fuc:N acetyl beta D glucosaminide alpha1,6 fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1; Glycoprotein 6 alpha L fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; 6)-fucosyltransferase; 6-fucosyltransferase.
literatures	Specific References  (1)     |     SL6280R has been referenced in 1 publications. [IF=2.571] Cheng Zhang. et al. Caveolin‐1 upregulates Fut8 expression by activating the Wnt/β‐catenin pathway to enhance HCC cell proliferative and invasive ability. Cell Biol Int. 2020 Nov;44(11):2202-2212  WB,IHC ;  Mouse.   PubMed:32710651
Research Area	Tumour  Cell biology  immunology  Signal transduction  TumourCell biologyMaker
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Pig, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	66kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FUT8: 311-410/575
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. There are 2 isoforms produced by alternative splicing. Immunogen is not present in isoform 2 (also known as Retinal). Function: Catalyzes the addition of fucose in alpha 1-6 linkage tocthe first GlcNAc residue, next to the peptide chains in N-glycans. Subcellular Location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Similarity: Belongs to the glycosyltransferase 23 family. Contains 1 SH3 domain. SWISS: Q9BYC5 Gene ID: 2530 Database links: Entrez Gene: 2530 Human Entrez Gene: 53618 Mouse Entrez Gene: 432392 Rat Omim: 602589 Human SwissProt: Q9BYC5 Human SwissProt: Q9WTS2 Mouse SwissProt: Q6EV76 Rat Unigene: 654961 Human Unigene: 35628 Mouse Unigene: 1717 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FUT8) Polyclonal Antibody, Unconjugated (SL6280R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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