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Rabbit Anti-LCMT1 antibody
Rabbit Anti-LCMT1 antibody
CGI 68; LCMT; LCMT1; LCMT1_HUMAN; Leucine carboxyl methyltransferase 1; PPMT1; Protein leucine O methyltransferase; Protein-leucine O-methyltransferase.
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Details

Product Name LCMT1
Chinese Name 亮氨酸羧基甲基转移酶1抗体
Alias CGI 68; LCMT; LCMT1; LCMT1_HUMAN; Leucine carboxyl methyltransferase 1; PPMT1; Protein leucine O methyltransferase; Protein-leucine O-methyltransferase.  
Research Area Tumour  Signal transduction  Kinases and Phosphatases  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 38kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LCMT1: 45-150/334 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915)

Function:
LCMT1, or leucine carboxyl methyltransferase 1, methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits (PPP2CA) to form alpha-leucine ester residues.

Similarity:
Belongs to the methyltransferase superfamily. LCMT family.

SWISS:
Q9UIC8

Gene ID:
51451

Database links:

Entrez Gene: 51451 Human

Omim: 610286 Human

SwissProt: Q9UIC8 Human

Unigene: 337730 Human



Product Picture
Sample: Cerebellum (Mouse) Lysate at 40 ug
Primary: Anti-LCMT1 (SL6249R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 38 kD

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