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Product Name LCMT1 Chinese Name 亮氨酸羧基甲基转移酶1抗体 Alias CGI 68; LCMT; LCMT1; LCMT1_HUMAN; Leucine carboxyl methyltransferase 1; PPMT1; Protein leucine O methyltransferase; Protein-leucine O-methyltransferase. Research Area Tumour Signal transduction Kinases and Phosphatases Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 38kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LCMT1: 45-150/334 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915)
Function:
LCMT1, or leucine carboxyl methyltransferase 1, methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits (PPP2CA) to form alpha-leucine ester residues.
Similarity:
Belongs to the methyltransferase superfamily. LCMT family.
SWISS:
Q9UIC8
Gene ID:
51451
Database links:Entrez Gene: 51451 Human
Omim: 610286 Human
SwissProt: Q9UIC8 Human
Unigene: 337730 Human
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