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Product Name GUK1 Chinese Name 鸟苷酸激酶GMK抗体 Alias GMK; GMP kinase; ATP:GMP phosphotransferase; FLJ42686; FLJ43710; GMK; Guanylate kinase; GUK1. Research Area Tumour Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Zebrafish, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 22kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GUK1/Guanylate kinase: 10-100/197 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene.
Function:
Essential for recycling GMP and indirectly, cGMP.
Subunit:
Monomer
Similarity:
Belongs to the guanylate kinase family.
Contains 1 guanylate kinase-like domain.
SWISS:
Q16774
Gene ID:
2987
Database links:
Entrez Gene: 281217 CowEntrez Gene: 2987 Human
Entrez Gene: 14923 Mouse
Omim: 139270 Human
SwissProt: Q16774 Human
SwissProt: Q64520 Mouse
Unigene: 376933 Human
Unigene: 3624 Mouse
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