TEL: +86 571 56623320 EMAIL: [email protected]
Product Name TLX3 Chinese Name T细胞白血病同源盒蛋白3抗体 Alias homeo box 11-like 2; Homeobox protein Hox 11L2; HOX11 L2; HOX11L2; RNX; T cell leukemia homeobox 3; TLX-3; T cell leukemia homeobox protein 3; TLX 3; TLX3_HUMAN. Research Area Tumour Chromatin and nuclear signals Signal transduction transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 32kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TLX3: 201-291/291 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.
Function:
Subcellular Location:
Nuclear
Similarity:
Contains 1 homeobox DNA-binding domain.
SWISS:
O43711
Gene ID:
30012
Database links:Entrez Gene: 30012 Human
Entrez Gene: 27140 Mouse
Omim: 604640 Human
SwissProt: O43711 Human
SwissProt: O55144 Mouse
Unigene: 249125 Human
Unigene: 25362 Mouse
Scan Wechat Qrcode