Product Name	VILIP1
Chinese Name	神经视锥蛋白样1(神经钙蛋白)抗体
Alias	VISL1_HUMAN; Visinin-like protein 1; Visinin like protein 1; Hippocalcin-like protein 3; visinin-like protein 1 isoform 3; Neurocalcin alpha; HLP3; HLP 3; HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1; VLP-1; VISL 1; VSNL1.
Research Area	Tumour  Cell biology  Neurobiology  Signal transduction  Binding protein  Alzheimer's
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human VILIP1: 121-191/191
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] Function: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. Tissue Specificity: Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level). Similarity: Belongs to the recoverin family. Contains 4 EF-hand domains. SWISS: P62760 Gene ID: 7447 Database links: Entrez Gene: 396189 Chicken Entrez Gene: 282124 Cow Entrez Gene: 7447 Human Entrez Gene: 26950 Mouse Entrez Gene: 24877 Rat Omim: 600817 Human SwissProt: P62764 Chicken SwissProt: P62763 Cow SwissProt: P62760 Human SwissProt: P62761 Mouse SwissProt: P62762 Rat Unigene: 444212 Human Unigene: 27005 Mouse Unigene: 105934 Rat
Product Picture	Sample: Recombinant human VILIP1 protein at 100 ng Primary: Anti-VILIP1 (SL6118R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 20 kD

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