Product Name	TUSC5
Chinese Name	抑癌基因5抗体
Alias	LOST1; Protein located at seventeen p thirteen point three 1; Tumor suppressor candidate 5; TUSC5_HUMAN.
Research Area	Tumour  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	19, 34kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TUSC5: 101-177/177
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	TUSC5 may be involved in fat metabolism. It is expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle and at lower levels in brain and lung. TUSC5 is strongly down regulated in lung cancer tissues, due to hypermethylation of the corresponding locus. Function: May be involved in fat metabolism Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus. Similarity: Belongs to the CD225/Dispanin family. SWISS: Q8IXB3 Gene ID: 286753 Database links: Entrez Gene: 286753 Human SwissProt: Q8IXB3 Human Unigene: 146059 Human

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