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Product Name TUSC3 Chinese Name 前列腺癌抑癌蛋白3抗体 Alias N33; OST3A; Protein N33; Putative prostate cancer tumor suppressor; Tumor suppressor candidate 3; TUSC-3; TUSC 3; TUSC3_HUMAN. Research Area Tumour immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Pig, Cow, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:200-800 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 34kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TUSC3: 201-300/348 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail TUSC3 belongs to the OST3/OST6 family of proteins and may be involved in N-glycosylation through its association with N-oligosaccharyl transferase. The TUSC3 gene is a candidate tumour supressor.
Subunit:
Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein (Probable).
Tissue Specificity:
Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.
Similarity:
Belongs to the OST3/OST6 family.
SWISS:
Q13454
Gene ID:
7991
Database links:Entrez Gene: 7991 Human
Entrez Gene: 80286 Mouse
Omim: 601385 Human
SwissProt: Q13454 Human
SwissProt: Q99J74 Mouse
Unigene: 591845 Human
Unigene: 35146 Rat
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