Product Name	RERG
Chinese Name	Ras相关雌激素调节生长抑制蛋白抗体
Alias	RAS like estrogen regulated growth inhibitor; Ras related and estrogen regulated growth inhibitor; Ras-related and estrogen-regulated growth inhibitor; Rerg; RERG_HUMAN; Weakly similar to N ras protein.
Research Area	Tumour  Chromatin and nuclear signals  Signal transduction  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Chicken, Dog, Cow, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RERG: 101-199/199
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation Function: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis. Similarity: Belongs to the small GTPase superfamily. Ras family. SWISS: Q96A58 Gene ID: 85004 Database links: Entrez Gene: 85004 Human Entrez Gene: 232441 Mouse Entrez Gene: 502916 Rat Omim: 612664 Human SwissProt: Q0VCJ7 Cow SwissProt: Q96A58 Human SwissProt: Q8R367 Mouse Unigene: 199487 Human Unigene: 46233 Mouse
Product Picture	Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti- RERG (SL6091R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 25 kD Paraformaldehyde-fixed, paraffin embedded (rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RERG) Polyclonal Antibody, Unconjugated (SL6091R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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