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Product Name LRP12 Chinese Name 低密度Lipoprotein受体相关蛋白12抗体(抑制Tumour蛋白7) Alias Low density lipoprotein receptor related protein 12; Low-density lipoprotein receptor-related protein 12; LRP 12; LRP-12; LRP12; LRP12_HUMAN; ST7; Suppressor of tumorigenicity 7 protein. Research Area Tumour Cardiovascular Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 91kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LRP12: 254-350/859 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
Function:
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
Subunit:
May interact with GNB2L1, ZFYVE9 and NMRK2
Subcellular Location:
Membrane; Single-pass type I membrane protein. Membrane, coated pit.
Tissue Specificity:
Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.
Similarity:
Belongs to the LDLR family.
Contains 2 CUB domains.
Contains 5 LDL-receptor class A domains.
SWISS:
Q9Y561
Gene ID:
29967
Database links:Entrez Gene: 29967 Human
Entrez Gene: 239393 Mouse
SwissProt: Q9Y561 Human
SwissProt: Q8BUJ9 Mouse
Unigene: 600630 Human
Unigene: 715867 Human
Unigene: 39874 Mouse
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