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Rabbit Anti-LRP12 antibody
Rabbit Anti-LRP12 antibody
Low density lipoprotein receptor related protein 12; Low-density lipoprotein receptor-related protein 12; LRP 12; LRP-12; LRP12; LRP12_HUMAN; ST7; Suppressor of tumorigenicity 7 protein.
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  • NO.:SL6071R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name LRP12
Chinese Name 低密度Lipoprotein受体相关蛋白12抗体(抑制Tumour蛋白7)
Alias Low density lipoprotein receptor related protein 12; Low-density lipoprotein receptor-related protein 12; LRP 12; LRP-12; LRP12; LRP12_HUMAN; ST7; Suppressor of tumorigenicity 7 protein.  
Research Area Tumour  Cardiovascular  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 91kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LRP12: 254-350/859 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.

Function:
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.

Subunit:
May interact with GNB2L1, ZFYVE9 and NMRK2

Subcellular Location:
Membrane; Single-pass type I membrane protein. Membrane, coated pit.

Tissue Specificity:
Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.

Similarity:
Belongs to the LDLR family.
Contains 2 CUB domains.
Contains 5 LDL-receptor class A domains.

SWISS:
Q9Y561

Gene ID:
29967

Database links:

Entrez Gene: 29967 Human

Entrez Gene: 239393 Mouse

Entrez Gene: 314941 Rat

SwissProt: Q9Y561 Human

SwissProt: Q8BUJ9 Mouse

Unigene: 600630 Human

Unigene: 715867 Human

Unigene: 39874 Mouse



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