Product Name	LRPAP1
Chinese Name	Lipoprotein受体相关蛋白/低密度Lipoprotein相关蛋白的相关蛋白1抗体
Alias	A2MRAP; A2RAP; Alpha 2 macroglobulin receptor associated protein; Alpha 2 MRAP; HBP44; Lipoprotein receptor associated protein; Low density lipoprotein receptor related protein associated protein 1; Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein; Low density lipoprotein related protein associated protein 1; LRPAP1; MRAP; RAP; AMRP_HUMAN.
Research Area	Cardiovascular  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Pig, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	38kDa
Cellular localization	cytoplasmic The cell membrane Extracellular matrix
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LRPAP1/MRAP: 131-330/357
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	A2MRAP; A2RAP; Alpha 2 macroglobulin receptor associated protein; Alpha 2 MRAP; HBP44; Lipoprotein receptor associated protein; Low density lipoprotein receptor related protein associated protein 1; Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein; Low density lipoprotein related protein associated protein 1; LRPAP1; MRAP; RAP. Function: Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. Subunit: Present on cell surface forming a complex with the alpha-2-macroglobulin receptor heavy and light chains. Binds LRP1B; binding is followed by internalization and degradation. Subcellular Location: Endoplasmic reticulum. Cytoplasm. Cell surface. Note=Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum. Post-translational modifications: N-glycosylated. DISEASE: Note=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis. Similarity: Belongs to the alpha-2-MRAP family. SWISS: P30533 Gene ID: 4043 Database links: Entrez Gene: 4043 Human Entrez Gene: 16976 Mouse Entrez Gene: 116565 Rat Omim: 104225 Human SwissProt: P30533 Human SwissProt: P55302 Mouse SwissProt: Q99068 Rat Unigene: 40966 Human Unigene: 533136 Human Unigene: 277661 Mouse Unigene: 10293 Rat
Product Picture	Sample: Hela (Human) Cell Lysate at 30 ug 293T (Human) Cell Lysate at 30 ug Primary: Anti- LRPAP1 (SL6055R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 38 kD

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