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Product Name PROCR/CD201 Chinese Name endothelial cells活化蛋白受体(CD201)抗体 Alias EPCR_HUMAN; Endothelial protein C receptor; EPCR; Activated protein C receptor (APC receptor); CD201; protein C receptor; CCCA; CCD41; Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications Flow-Cyt=1:50-1:100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 25kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml Lsotype IgG1/Kappa Purification Affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
SWISS:
Q9UNN8
Gene ID:
10544
Database links:Entrez Gene: 10544 Human
Omim: 600646 Human
SwissProt: Q9UNN8 Human
Unigene: 647450 Human
结合活化蛋白C。通过凝血酶-血栓调节蛋白复合物增强蛋白C的活化;在控制凝血的蛋白C途径中起作用。Product Picture Cell line: HUVEC
Fixative: Unfixed
Permeabilization: None
Primary Ab dilution: 1:100
Secondary Ab: Goat anti Rat IgG
Unlabelled control: The cell without incubation with primary antibody and secondary antibody (Black line).
Isotype control: Rat monoclonal IgG1 (Blue line).
Comment: Line red is the positive signal for SL60546R
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