Product Name	FSTL1
Chinese Name	卵泡抑素相关蛋白1抗体
Alias	FSTL1; TSC-36; Follistatin like 1; Follistatin related protein; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1_HUMAN.
Research Area	Cardiovascular  Cell biology  Cyclin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FSTL1/FRP: 201-308/308
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	TSC-36 is a secreted extracellular glycoprotein. The amino acid sequence of TSC-36 is similar to follistatin, an inhibitor of activin, as it contains a follistatin module. TSC-36 is a heparin-binding protein suggested to have a role in the negative regulation of cellular growth, as its expression is induced in response to TGF-b1. In addition, TSC-36 is not found in small cell lung cancer (SCLC) cells, a highly aggressive neoplasm, but is detected in some non-small cell lung cancer (NSCLC) cells, a moderately aggressive neoplasm.. May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin. Function: May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin. Subunit: Interacts with SCN10A. Subcellular Location: Secreted. Tissue Specificity: Overexpressed in synovial tissues from rheumatoid arthritis. Similarity: Contains 2 EF-hand domains. Contains 1 follistatin-like domain. Contains 1 Kazal-like domain. Contains 1 VWFC domain. SWISS: Q12841 Gene ID: 534482 Database links: Entrez Gene: 534482 Cow Entrez Gene: 11167 Human Entrez Gene: 14314 Mouse Entrez Gene: 79210 Rat Omim: 605547 Human SwissProt: Q58D84 Cow SwissProt: Q12841 Human SwissProt: Q62356 Mouse SwissProt: Q62632 Rat Unigene: 269512 Human Unigene: 182434 Mouse Unigene: 95652 Rat
Product Picture	Sample: Lane 1: Human U-2 OS cell lysates Lane 2: Human HeLa cell lysates Lane 3: Human HUVEC cell lysates Lane 4: Human A431 cell lysates Primary: Anti-FSTL1 (SL6050R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kDa Observed band size: 47 kDa

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