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Product Name ASAM Chinese Name 脂肪细胞特异性粘附分子抗体 Alias ACAM; Adipocyte specific adhesion molecule; CAR like membrane protein; CLMP; Coxsackie and adenovirus receptor like membrane protein; CLMP_HUMAN. literatures Specific References (1) | SL6022R has been referenced in 1 publications.[IF=6.792] Zhao D et al. PCB52 exposure alters the neurotransmission ligand-receptors in male offspring and contributes to sex-specific neurodevelopmental toxicity. Environ Pollut.2020 Sep;264:114715. WB ; Rat.Research Area immunology Signal transduction Cell Surface Molecule Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 39kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ASAM/ACAM: 15-110/373 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The CTX family of proteins, including ASAM, are type I transmembrane proteins within the Ig superfamily that localize to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion.
Function:
May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity.
Subunit:
Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein (Potential).
Subcellular Location:
Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:
Predominantly expressed in epithelial cells within different tissues and in the white adipose tissue. Expressed at high levels in small intestine and placenta, at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney and lung and at low levels in the liver and peripheral blood leukocytes.
Similarity:
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
Q9H6B4
Gene ID:
79827
Database links:Entrez Gene: 79827 Human
Entrez Gene: 71566 Mouse
Omim: 611693 Human
SwissProt: Q9H6B4 Human
SwissProt: Q8R373 Mouse
Unigene: 591949 Human
Unigene: 280560 Mouse
Unigene: 163013 Rat
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