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Rabbit Anti-LETMD1 antibody
Rabbit Anti-LETMD1 antibody
LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2; LTMD1_HUMAN; HCCR 2; HCCR2.
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  • NO.:SL5937R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name LETMD1
Chinese Name 宫颈癌原癌基因2抗体
Alias LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2; LTMD1_HUMAN; HCCR 2; HCCR2.  
Research Area Tumour  immunology  TumourCell biologyMaker  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 40kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HCCR2/LETMD1: 21-120/360 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011].

Function:
Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.

Subunit:
Interacts with BRI3BP.

Subcellular Location:
Mitochondrion outer membrane; Single-pass membrane protein.

Tissue Specificity:
Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix.

Similarity:
Contains 1 LETM1 domain.

SWISS:
Q6P1Q0

Gene ID:
25875

Database links:

Entrez Gene: 25875 Human

Entrez Gene: 68614 Mouse

SwissProt: A3KN46 Cow

SwissProt: Q6P1Q0 Human

SwissProt: Q924L1 Mouse

Unigene: 655272 Human

Unigene: 275272 Mouse



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