Product Name	GCET1
Chinese Name	Blymphocyte生发中心相关蛋白抗体
Alias	Centerin; GCET1; Germinal center B cell expressed transcript 1; Seprin A9; Serine proteinase inhibitor A11; SERPINA11; SERPINA11b; SERPINA9.
Research Area	Tumour  Cell biology  immunology  b-lymphocyte
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	43kDa
Cellular localization	cytoplasmic Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GCET1: 301-400/417
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	GCET1 (germinal center B-cell expressed transcript 1) belongs to the SERPIN family of proteins and is located within a cluster of SERPIN genes on chromosome 14q32). GCET1 is a protease inhibitor that inhibits trypsin and trypsin-like serine proteases in virto, and to a lesser extent inhibits plasmin and thrombin. This protein may play an important role in GC-B cell physiology. Its expression in lymphomas could be important in differential diagnosis and research. Subcellular Location: Isoform 1: Secreted. Isoform 2, 3, 4, 5, 6, 7: Cytoplasm (Probable). Tissue Specificity: Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies. Similarity: Belongs to the serpin family. SWISS: Q86WD7 Gene ID: 327657 Database links: Entrez Gene: 327657 Human SwissProt: Q86WD7 Human Unigene: 317970 Human

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