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Product Name Annexin A9 Chinese Name 膜粘连蛋白9抗体 Alias annexin 31; annexin A9; annexin XXXI; ANX31; ANXA9; ANXA 9; ANXA-9; pemphaxin; ANXA9_HUMAN . Research Area Cell biology immunology Cell adhesion molecule Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 38kDa Cellular localization cytoplasmic Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Annexin A9: 261-345/345 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ANXA9 may act as a low affinity receptor for acetylcholine and is expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). ANXA9 is one of the target molecules recognized by autoantibodies in patients with pemphigus vulgaris, a rare, autoimmune skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion.
Function:
Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.
Subunit:
Homodimer.
Tissue Specificity:
Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level).
Similarity:
Belongs to the annexin family.
Contains 4 annexin repeats.
SWISS:
O76027
Gene ID:
8416
Database links:Entrez Gene: 8416 Human
Entrez Gene: 71790 Mouse
Omim: 603319 Human
SwissProt: O76027 Human
SwissProt: Q9JHQ0 Mouse
Unigene: 3346 Human
Unigene: 218844 Mouse
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