Product Name	DLL4
Chinese Name	DeltaD抗体
Alias	DeltaD; delta4; delta-like 4 (Drosophila); delta-like 4 homolog (Drosophila); Drosophila Delta homolog 4; delta-like 4 homolog; delta-like 4 protein; Aei; After eight; dld; DLL4_HUMAN; Delta-like protein 4; Drosophila Delta homolog 4; Delta 4 precursor; delta 4; delta ligand 4; notch ligand delta-2; hdelta2; MGC126344; notch ligand DLL4.
Research Area	immunology  Developmental biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	75kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DLL4: 551-650/685
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DeltaD is one of the 4 members of the zebrafish Delta family of Notch ligands, important in the control of cell differentiation in many tissues. DeltaD acts as a ligand for Notch receptors and is involved in primary neurogenesis and somitogenesis. It can activate Notch receptors, thereby playing a key role in lateral inhibition, a process that prevents the immediate neighbors of each nascent neural cell from simultaneously embarking on neural differentiation. It is required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized. Function: Cell surface proteoglycan that bears heparan sulfate. Required for cell division patterning during post-embryonic development of the nervous system. Subcellular Location: Cell membrane. Similarity: Belongs to the glypican family. SWISS: Q9NR61 Gene ID: 54567 Database links: Entrez Gene: 54567 Human Entrez Gene: 54485 Mouse Entrez Gene: 311332 Rat Omim: 605185 Human SwissProt: Q9NR61 Human SwissProt: Q9JI71 Mouse Unigene: 511076 Human Unigene: 143719 Mouse
Product Picture	Sample: Lane 1: Human K562 cell Lysates Lane 2: Human THP-1 cell Lysates Lane 3: Human 293T cell Lysates Primary: Anti-DLL4 (SL5909R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75kDa Observed band size: 75kDa Sample: Lung (Rat) Lysate at 40 ug Primary: Anti-DLL4 (SL5909R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75 kD Observed band size: 75 kD

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