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Product Name ADAMTSL1 Chinese Name 整合素样金属蛋白酶与凝血酶样1蛋白抗体 Alias ADAM TS related protein 1; ADAMTS like 1; ADAMTSR 1; C9orf94; Chromosome 9 open reading frame 94; Punctin 1; Punctin; Thrombospondin; ATL1_HUMAN. Research Area Tumour Cell biology immunology Signal transduction Cell adhesion molecule Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 190kDa Cellular localization Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ADAMTSL1: 1201-1300/1762 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins.
Subcellular Location:
Secreted > extracellular space > extracellular matrix.
Tissue Specificity:
Expressed primarily in adult skeletal muscle.
Post-translational modifications:
Glycosylated.
Disulfide bonds are present.
Similarity:
Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 PLAC domain.
Contains 9 TSP type-1 domains.
SWISS:
Q8N6G6
Gene ID:
92949
Database links:Entrez Gene: 92949 Human
Entrez Gene: 77739 Mouse
Omim: 609198 Human
SwissProt: Q8N6G6 Human
SwissProt: Q8BLI0 Mouse
Unigene: 741483 Human
Unigene: 331690 Mouse
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