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Product Name ANKHD1 Chinese Name 艾滋病病毒制约锚定蛋白抗体 Alias ANKH1_HUMAN; ANKHD 1; ANKHD1; Ankyrin repeat and KH domain containing 1; Ankyrin repeat and KH domain containing protein 1; Ankyrin repeat and KH domain-containing protein 1; HIV-1 Vpr-binding ankyrin repeat protein; HIV1 Vpr binding ankyrin repeat protein; hMASK; MASK; Multiple ankyrin repeats single KH domain; Multiple ankyrin repeats single KH domain homolog; VBARP. literatures Specific References (1) | SL5831R has been referenced in 1 publications.[IF=6.083] Sun, Wenhuizi. et al. Alternative ANKHD1 transcript promotes proliferation and inhibits migration in uterine corpus endometrial carcinoma. NPJ GENOM MED. 2022 Sep;7(1):1-12 IF ; Human.Research Area Tumour Cell biology immunology Bacteria and viruses Cell adhesion molecule Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Dog, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 269kDa Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ANKHD1: 1901-2000/2542 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.
Function:
May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.
Subunit:
Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain.
Similarity:
Belongs to the mask family.
Contains 25 ANK repeats.
Contains 1 KH domain.
SWISS:
Q8IWZ3
Gene ID:
54882
Database links:Entrez Gene: 54882 Human
Omim: 610500 Human
SwissProt: Q8IWZ3 Human
Unigene: 594084 Human
Unigene: 720987 Human
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