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Rabbit Anti-RELM beta antibody
Rabbit Anti-RELM beta antibody
Resistin like protein beta; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 2; CCGR; Colon and small intestine specific cysteine rich protein; Colon and small intestine-specific cysteine-rich protein; Colon carcinoma rela
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Details

Product Name RELM beta
Chinese Name 抵抗素样分子β抗体
Alias Resistin like protein beta; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 2; CCGR; Colon and small intestine specific cysteine rich protein; Colon and small intestine-specific cysteine-rich protein; Colon carcinoma related gene protein; Colon carcinoma-related gene protein; Cysteine rich secreted A12 alpha like protein 1; Cysteine rich secreted protein A12 alpha like 1; Cysteine rich secreted protein FIZZ2; Cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein FIZZ2; FIZZ1; FIZZ2; Found in inflammatory zone 1; Found in Inflammatory Zone 2; HXCP2; RELM beta; RELMb; RELMbeta; Resistin like beta; Resistin Like Protein Beta; Resistin-like beta; RETNB_HUMAN; RETNL2. RETNLB; XCP2.  resistin-like β;
literatures
Specific References  (1)     |     SL5774R has been referenced in 1 publications.
[IF=13.116] Andong Zhao. et al. Chemical conversion of human epidermal stem cells into intestinal goblet cells for modeling mucus-microbe interaction and therapy. Sci Adv. 2021 Apr;7(16):eabb2213  ICC ;  Human.  
Research Area Tumour  immunology  Signal transduction  Growth factors and hormones  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 9kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RELM beta : 24-80/111 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin, also known as ADSF) is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

Function:
Probable hormone.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed only in the gastrointestinal tract, particularly the colon.

Similarity:
Belongs to the resistin/FIZZ family.

SWISS:
Q9BQ08

Gene ID:
84666

Database links:

Entrez Gene: 84666 Human

Omim: 605645 Human

SwissProt: Q9BQ08 Human

Unigene: 307047 Human



Product Picture
Paraformaldehyde-fixed, paraffin embedded (human stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RELM beta) Polyclonal Antibody, Unconjugated (SL5774R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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