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Product Name FGF22 Chinese Name 成纤维细胞生长因子22抗体 Alias FGF 22; FGF-22; FGF22; FGF22_HUMAN; Fibroblast growth factor 22; si:dkey 21e2.2. Research Area Tumour Cardiovascular immunology Signal transduction Growth factors and hormones Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 17kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FGF22.: 23-100/170 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FGF22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Fibroblast Growth Factor-22 stimulates the proliferation and activation of cells that express FGF receptor.
Function:
Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.
Subunit:
Interacts with FGFR1 and FGFR2. Interacts with FGFBP1.
Subcellular Location:
Secreted (Potential).
Similarity:
Belongs to the heparin-binding growth factors family.
SWISS:
Q9HCT0
Gene ID:
27006
Database links:Entrez Gene: 27006 Human
Entrez Gene: 67112 Mouse
Omim: 605831 Human
SwissProt: Q9HCT0 Human
SwissProt: Q9ESS2 Mouse
Unigene: 248087 Human
Unigene: 154211 Mouse
Unigene: 198777 Rat
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