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Product Name MRP9 Chinese Name 多药耐药相关蛋白9抗体 Alias ABCC 12; Abcc12; ATP binding cassette sub family C (CFTR MRP) member 12; ATP binding cassette protein C12; ATP binding cassette transporter sub family C member 12; ATP binding cassette, sub family C, member 12; ATP-binding cassette sub-family C member 12; MRP9; MRP9_HUMAN; Multidrug resistance associated protein 9; Multidrug resistance-associated protein 9. literatures Specific References (1) | SL5763R has been referenced in 1 publications.[IF=3.998] Chika Miyagi-Shiohira. et al. Kyoto probe-1 reveals phenotypic differences between mouse ES cells and iTS-P cells. Sci Rep-Uk. 2020 Oct;10(1):1-13 IHC ; Mouse.Research Area Tumour immunology Signal transduction transcriptional regulatory factor Transporter Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 152kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MRP9/ABCC12: 861-960/1359 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
Function:
Probable transporter (By similarity).
Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).
Tissue Specificity:
Expressed in testis (at protein level). Widely expressed at low level. Isoform 5 is specifically expressed in brain, testis and breast cancer cells.
Similarity:
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.
SWISS:
Q96J65
Gene ID:
94160
Database links:Entrez Gene: 94160 Human
Omim: 607041 Human
SwissProt: Q96J65 Human
Unigene: 410111 Human
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