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Product Name MRP7 Chinese Name 多药耐药相关蛋白7抗体 Alias ABCC10; ATP binding cassette, sub family C (CFTR/MRP), member 10; ATP binding cassette, subfamily C, member 10; ATP-binding cassette sub-family C member 10; EST182763; mFLJ00002; MRP7; MRP7_HUMAN; Multidrug resistance associated protein 7; Multidrug resistance-associated protein 7; SIMRP7; SIMRP7. Research Area Tumour immunology Signal transduction Channel protein The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 162kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MRP7/ABCC10.: 1401-1492/1492 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
Function:
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
Similarity:
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.
SWISS:
Q5T3U5
Gene ID:
89845
Database links:Entrez Gene: 89845 Human
Omim: 612509 Human
SwissProt: Q5T3U5 Human
Unigene: 55879 Human
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