Product Name	RASL10A
Chinese Name	Ras样蛋白家族10A抗体
Alias	Ras like protein family member 10A; Ras like protein RRP22; RAS like, family 10, member A; RAS related on chromosome 22; Ras related protein on chromosome 22; Ras related protein on chromosome 22 homolog; RASL10A protein; Rasl10a RAS like, family 10, member A; RP23 64E17.6 antibody RRP22; RSLAA_HUMAN.
Research Area	Tumour  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23kDa
Cellular localization	The nucleus cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RASL10A: 51-150/203
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Ras proteins are members of a superfamily of related small GTPases. RRP22 can be posttranslationally modified by farnesyl. RRP22 inhibits cell growth and promotes caspase-independent cell death. The specific function of RASL10A is not yet known. Function: Potent inhibitor of cellular proliferation. Subunit: Interacts with UBF/UBTF. Subcellular Location: Cell membrane, Cytoplasmic side. Nucleus, nucleolus. Note=May cycle in and out of the nucleolus in a GTP-dependent manner. Tissue Specificity: Expression appears to be strictly limited to the central nervous system. Post-translational modifications: Isoprenylation is essential for nucleolar localization, and the proliferation-inhibiting activity of RASL10A. Similarity: Belongs to the small GTPase superfamily. Ras family. SWISS: Q92737 Gene ID: 10633 Database links: Entrez Gene: 10633 Human Entrez Gene: 75668 Mouse Entrez Gene: 364190 Rat Omim: 602220 Human SwissProt: Q92737 Human SwissProt: Q8K5A4 Mouse Unigene: 73088 Human Unigene: 374836 Mouse Unigene: 50230 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RASL10A) Polyclonal Antibody, Unconjugated (SL5722R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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