Product Name	PTPIP51
Chinese Name	蛋白酪氨酸磷酸酶相互作用蛋白51抗体
Alias	Cerebral protein 10; Family with sequence similarity 82 member C; hRMD 3; Microtubule associated protein; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase interacting protein 51; PTPIP51; Regulator of microtubule dynamics 3; Regulator of microtubule dynamics protein 3; RMD 3; RMD3; TCPTP interacting protein 51; RMDN3; RMD3_HUMAN.
Research Area	Tumour  Cell biology  immunology  Cyclin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	52kDa
Cellular localization	The nucleus cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PTPIP51/FAM82A2: 101-180/470
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	RMDN3 (Regulator Of Microtubule Dynamics 3) is a Protein Coding gene. Diseases associated with RMDN3 include Amyotrophic Lateral Sclerosis 16, Juvenile and Amyotrophic Lateral Sclerosis 8. An important paralog of this gene is RMDN2. Function: Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis. Subunit: Interacts with PTPN2. Interacts with microtubules. Interacts with VAPB. Subcellular Location: Mitochondrion membrane; Single-pass membrane protein. Mitochondrion outer membrane. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. Tissue Specificity: Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed. Similarity: Belongs to the RMDN family. SWISS: Q96TC7 Gene ID: 55177 Database links: Entrez Gene: 55177 Human Entrez Gene: 100172768 Orangutan Omim: 611873 Human SwissProt: Q96TC7 Human SwissProt: Q5R6Z1 Orangutan
Product Picture	Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Human U251 cell lysates Primary: Anti- PTPIP51 (SL5719R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD

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