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Rabbit Anti-ALDH1L1 antibody
Rabbit Anti-ALDH1L1 antibody
AL1L1_HUMAN; Cytosolic 10-formyltetrahydrofolate dehydrogenase; Aldehyde dehydrogenase family 1 member L1; FTHFD; EC:1.5.1.6; 10-FTHFDH; FDH; 10-fTHF;
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  • NO.:SL5709R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Dog,Pig,Horse,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name ALDH1L1
Chinese Name 乙醛脱氢酶1蛋白家族L1抗体
Alias AL1L1_HUMAN; Cytosolic 10-formyltetrahydrofolate dehydrogenase; Aldehyde dehydrogenase family 1 member L1; FTHFD; EC:1.5.1.6; 10-FTHFDH; FDH; 10-fTHF;   
Research Area Tumour  Neurobiology  Signal transduction  Apoptosis  Cell adhesion molecule  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Dog, Pig, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 100kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ALDH1L1: 451-550/902 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Highly expressed in liver, pancreas and kidney.

SWISS:
O75891

Gene ID:
10840

Database links:

Entrez Gene: 10840 Human

Entrez Gene: 107747 Mouse

Entrez Gene: 100622210 Pig

Entrez Gene: 64392 Rat

SwissProt: O75891 Human

SwissProt: Q8R0Y6 Mouse

SwissProt: P28037 Rat



Product Picture
Tissue/cell: Rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-ALDH1L1 Polyclonal Antibody, Unconjugated(SL5709R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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