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Product Name phospho-NPTX1 (Tyr344) Chinese Name 磷酸化神经细胞正五聚体1抗体 Alias NPTX1(phospho Tyr344); NPTX1(phospho Y344); Neuronal pentraxin I; Neuronal pentraxin-1; NP 1; NP-I; NP1; Nptx1; NPTX1_HUMAN. Product Type Phosphorylated anti Research Area immunology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 45kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated Synthesised phosphopeptide derived from human NPTX1 around the phosphorylation site of Tyr344: AP(p-Y)HP Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.
Function:
May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin (By similarity).
Subcellular Location:
Cytoplasmic vesicle, secretory vesicle (Potential).
Similarity:
Contains 1 pentaxin domain.
SWISS:
Q15818
Gene ID:
4884
Database links:Entrez Gene: 4884 Human
Entrez Gene: 18164 Mouse
Omim: 602367 Human
SwissProt: Q15818 Human
SwissProt: Q62443 Mouse
Unigene: 514556 Human
Unigene: 719680 Human
Unigene: 5142 Mouse
Unigene: 54707 Rat
Product Picture Sample:
Hippocampus (Mouse) Lysate at 40 ug
Primary: Anti- phospho-NPTX1 (Tyr344) (SL5527R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 45 kD
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