Product Name	Phospho-ATG4C (Ser398)
Chinese Name	磷酸化自噬相关蛋白4C抗体
Alias	Phospho-ATG4C (Ser398); Phospho-ATG4C (S398); APG4 autophagy 4 homolog C (S. cerevisiae); APG4 autophagy 4 homolog C; APG4 C; APG4-C; APG4C; ATG 4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); Atg4c; ATG4C_HUMAN; AUT (S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase (S. cerevisiae); AUT like 1, cysteine endopeptidase; AUT like 3 cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; Autophagin 3; Autophagin-3; Autophagy related cysteine endopeptidase 3; Autophagy related protein 4 homolog C; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; Cysteine protease ATG4C; EC 3.4.22; FLJ14867; OTTHUMP00000010715.
Product Type	Phosphorylated anti
Research Area	Tumour  Cardiovascular  Cell biology  immunology  Signal transduction  Apoptosis  Kinases and Phosphatases  Mitochondrion  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	52kDa
Cellular localization	The nucleus cytoplasmic Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated Synthesised phosphopeptide derived from human ATG4C around the phosphorylation site of Ser398: RA(p-S)EE
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Function: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Subcellular Location: Cytoplasm (Probable). Tissue Specificity: Highly expressed in skeletal muscle, heart, liver and testis. Similarity: Belongs to the peptidase C54 family. SWISS: Q96DT6 Gene ID: 84938 Database links: Entrez Gene: 84938 Human Entrez Gene: 242557 Mouse Entrez Gene: 313391 Rat Omim: 611339 Human SwissProt: Q96DT6 Human SwissProt: Q811C2 Mouse Unigene: 7353 Human Unigene: 241663 Mouse Unigene: 23378 Rat
Product Picture	Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-Phospho-ATG4C(Ser398) (SL5205R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 55 kD

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