Product Name	SLCO2A1
Chinese Name	溶质载体蛋白家族21成员2抗体
Alias	MATR1; Matrin F/G 1; OATP2A1; PGT; SO2A1_HUMAN; PHOAR2; Prostaglandin transporter; SLC21A2; Solute carrier family 21 (prostaglandin transporter) member 2; Solute carrier family 21 member 2; Solute carrier organic anion transporter family member 2A1.
literatures	Specific References  (1)     |     SL4710R has been referenced in 1 publications. [IF=2.74] Nanase Takahashi. et al. Up-regulation of cytosolic prostaglandin E synthase in fetal-membrane and amniotic prostaglandin E2 accumulation in labor. Plos One. 2021 Apr;16(4):e0250638  IHC ;  Human.   PubMed:33891661
Research Area	Cell biology  immunology  Signal transduction  Channel protein  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=3ug/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	70kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PGT/Slco2a1: 611-643/643 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The organic anion transporting polypeptide (OATP) family of proteins play a role in drug absorption, distribution and excretion. OATP proteins mediate the uptake of a broad range of substrates, including bile salts, hormones, drugs and antibiotics, and they are expressed in various tissues, such as gut, brain, kidney and liver. PGT, also known as SLCO2A1 (solute carrier organic anion transporter family, member 2A1), SLC21A2 or OATP2A1, is a 643 amino acid multi-pass membrane protein that belongs to the organic anion transporter family. Expressed ubiquitously, PGT is thought to mediate the release, transepithelial transport and clearance of prostaglandins from cells to other areas of the body. The gene encoding PGT maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Function: May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Ubiquitous. Similarity: Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain. SWISS: Q92959 Gene ID: 6578 Database links: Entrez Gene: 6578 Human Omim: 601460 Human SwissProt: Q92959 Human Unigene: 518270 Human
Product Picture	Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-SLCO2A1 (SL4710R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70 kD Observed band size: 75 kD Blank control: Mouse kidney. Primary Antibody (green line): Rabbit Anti-SLCO2A1 antibody (SL4710R) Dilution: 3μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.

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