Product Name	AMH
Chinese Name	Muellerian缪勒管激素抑制因子抗体
Alias	MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance.
literatures	Specific References  (4)     |     SL4687R has been referenced in 4 publications. [IF=11.459] Su Zhouet al. Ovarian Dysfunction Induced by Chronic Whole‐Body PM2.5 Exposure. Small . 2020 Aug;16(33):e2000845.  ELISA ;  mouse.   PubMed:10.1002/smll.202000845 [IF=6.183] Shan Zhang. et al. Early evaluation of survival of the transplanted ovaries through ultrasound molecular imaging via targeted nanobubbles. Biomater Sci-Uk. 2020 Sep;8(19):5402-5414  WB,IF ;  Rat.   PubMed:32996915 [IF=4.384] Jiao-jiao ZHANG. et al. Cold plasma promotes Sertoli cell proliferation via AMPK-mTOR signaling pathway1. J INTEGR AGR. 2022 Jul;:  IF ;  Chicken.   PubMed:10.1016/j.jia.2022.07.010 [IF=2.984] Wang W et al. Amh dominant expression in Sertoli cells during the testicular differentiation and development stages in the olive flounder Paralichthys olivaceus. Gene . 2020 Sep 10;755:144906.  IHC ;  flounder.   PubMed:32554048
Research Area	Tumour  Cell biology  Developmental biology  Signal transduction  Stem cells  Growth factors and hormones  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	57kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human AMH: 501-560/560
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]. Function: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted. DISEASE: Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the TGF-beta family. SWISS: P03971 Gene ID: 268 Database links: Entrez Gene: 268 Human Entrez Gene: 11705 Mouse Entrez Gene: 25378 Rat Omim: 600957 Human SwissProt: P03971 Human SwissProt: P27106 Mouse SwissProt: P49000 Rat Unigene: 112432 Human Unigene: 19121 Rat

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