Product Name	Mammaglobin A
Chinese Name	乳腺珠蛋白1抗体
Alias	Mammaglobin 1; Mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB 1; MGB1; Prostatein C3 subunit; prostatein peptide C3; Prostatic steroid binding protein, allele C3(1); SCGB2A2; Secretoglobin; Secretoglobin Family 2A Member 2; SG2A2; UGB 2; UGB2; Uteroglobin; Psbpc3.
literatures	Specific References  (1)     |     SL4684R has been referenced in 1 publications. [IF=3.743] Ying Liu. et al. 1H-NMR based metabolic study of MMTV-PyMT mice along with pathological progress to screen biomarkers for early diagnosis of breast cancer. Mol Omics. 2021 Dec;:  IHC ;  Mouse.   PubMed:34918730
Research Area	Tumour  Cell biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Mouse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	8.4kDa
Cellular localization	Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse Mammaglobin A: 41-96/96
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. Tissue Specificity: Mammary gland specific. Over-expressed in breast cancer. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. SWISS: Q13296 Gene ID: 4250 Database links: Entrez Gene: 4250 Human Entrez Gene: 100040203 Mouse Entrez Gene: 361725 Rat Omim: 605562 Human SwissProt: Q13296 Human Unigene: 46452 Human 乳腺球蛋白是一个乳腺相关glycoprotein，它是一个分泌素家族（包括子宫球蛋白和lipophilin）成员的远亲。与其他分泌素家族成员不同，乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中，该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时，检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白，在鉴定原发癌是否发生转移中起到至关重要的作用。

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