Product Name	Layilin
Chinese Name	透明质酸受体抗体
Alias	Layn; E030012M19Rik; Gm511; LAYN_HUMAN.
Research Area	Tumour  Cell biology  immunology  transcriptional regulatory factor  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Layilin: 281-382/382
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	LAYN is integral membrane protein, and a hyaluronate receptor. It has been shown to bind specifically to hyaluronan but not to other glycosaminoglycans. It is a recently characterized transmembrane protein with homology to C type lectins, and is a membrane binding site for talin in peripheral ruffles of spreading cells. LAYN may have a role in cell adhesion and motility. Function: Receptor for hyaluronate. Subcellular Location: Membrane. Colocalizes with TLN1 at the membrane ruffles. SWISS: Q6UX15 Gene ID: 143903 Database links: Entrez Gene: 143903 Human Entrez Gene: 244864 Mouse Entrez Gene: 500996 Rat SwissProt: Q6UX15 Human SwissProt: Q8C351 Mouse Unigene: 503831 Human Unigene: 335152 Mouse Unigene: 230868 Rat Layilin是一种新发现的特异性透明质酸受体蛋白，目前主要用于肺部Tumour方面的研究。

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