Product Name	NXPH4
Chinese Name	神经外营养蛋白4抗体
Alias	Neurexophilin 4; NPH4; NXPH 4.
Research Area	Cell biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	33kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NXPH4: 241-308/308
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	NXPH4 is a neurexophilin. Mammalian brains contain four different neurexophilin proteins. Neurexophilins form a family of related glycoproteins that are proteolytically processed after synthesis and bind to alpha neurexins. The structure and characteristics of neurexophilins indicate that they function as neuropeptides that may signal via alpha neurexins and possibly other receptors. Function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Subcellular Location: Secreted. Tissue Specificity: Expressed in brain, spleen, and testis. Post-translational modifications: May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells. Similarity: Belongs to the neurexophilin family. SWISS: O95158 Gene ID: 11247 Database links: Entrez Gene: 11247 Human Entrez Gene: 59316 Rat Omim: 604637 Human SwissProt: O95158 Human SwissProt: Q9Z2N4 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NXPH4) Polyclonal Antibody, Unconjugated (SL4411R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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