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Rabbit Anti-NUFIP2 antibody
Rabbit Anti-NUFIP2 antibody
82 kDa FMRP-interacting protein; 82-FIP; Cell proliferation-inducing gene 1 protein; FMRP-interacting protein 2; Nuclear fragile X mental retardation-interacting protein 2; NUFIP2; NUFP2_HUMAN.
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  • NO.:SL4403R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Rabbit,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name NUFIP2
Chinese Name NUFIP2蛋白抗体
Alias 82 kDa FMRP-interacting protein; 82-FIP; Cell proliferation-inducing gene 1 protein; FMRP-interacting protein 2; Nuclear fragile X mental retardation-interacting protein 2; NUFIP2; NUFP2_HUMAN.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 76kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NUFIP2: 101-200/695 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail NUFIP2 (NUFIP2, FMR1 Interacting Protein 2) is a Protein Coding gene. Diseases associated with NUFIP2 include Chromosome 17Q11.2 Deletion Syndrome, 1.4-Mb and Chromosome 17Q11.2 Deletion Syndrome. GO annotations related to this gene include poly(A) RNA binding and RNA binding.

Function:
Binds RNA.

Subcellular Location:
Nucleus. Cytoplasm. Distribution is cell cycle-modulated, being cytoplasmic in the G2/M phase and accumulating in nucleus during the G1 phase.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

SWISS:
Q7Z417

Gene ID:
57532

Database links:

Entrez Gene: 57532 Human

Entrez Gene: 68564 Mouse

Omim: 609356 Human

SwissProt: Q7Z417 Human

SwissProt: Q5F2E7 Mouse

Unigene: 462598 Human

Unigene: 428996 Mouse



Product Picture
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NUFIP2) Polyclonal Antibody, Unconjugated (SL4403R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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