Product Name	Growth Arrest Specific Protein 7
Chinese Name	生长休止特定蛋白7抗体
Alias	GAS 7; GAS-7; Gas7; GAS7_HUMAN; Growth arrest specific 7; Growth arrest-specific protein 7; KIAA0394; MGC1348; MLL/GAS7; MLL/GAS7 fusion protein.
Research Area	Tumour  Cell biology  immunology  Chromatin and nuclear signals  Signal transduction  Cyclin  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	54kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GAS7/Growth Arrest Specific Protein 7: 361-476/476
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Growth arrest specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. It may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Several transcript variants encoding proteins which vary in the N terminus have been described. Function: May play a role in promoting maturation and morphological differentiation of cerebellar neurons. Subcellular Location: Cytoplasm (By similarity). DISEASE: Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. Similarity: Contains 1 FCH domain. Contains 1 SH3 domain. Contains 1 WW domain. SWISS: O60861 Gene ID: 8522 Database links: Entrez Gene: 8522 Human Omim: 603127 Human SwissProt: O60861 Human SwissProt: O55148 Rat Unigene: 258855 Human Unigene: 462214 Human Unigene: 17160 Rat

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