Product Name	TM7SF2
Chinese Name	脱氢胆固醇还原酶14抗体
Alias	ANG1; Another new gene 1 protein; DHCR14A; C 14 sterol reductase; C-14 sterol reductase; Delta 14 SR; Delta(14) sterol reductase; Delta(14)-sterol reductase; Delta-14-SR; DHCR14A; ERG24_HUMAN; NET47; Putative sterol reductase SR 1; Putative sterol reductase SR-1; Sterol C14 reductase; Sterol C14-reductase; TM7SF2; Transmembrane 7 superfamily member 2.
Research Area	Tumour  Cardiovascular  Cell biology  immunology  Chromatin and nuclear signals  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Cow, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	46kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TM7SF2/DHCR14A: 51-150/418
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. Function: Involved in the conversion of lanosterol to cholesterol. Subcellular Location: Microsome membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. Similarity: Belongs to the ERG4/ERG24 family. SWISS: O76062 Gene ID: 7108 Database links: Entrez Gene: 7108 Human Entrez Gene: 73166 Mouse Entrez Gene: 293688 Rat Omim: 603414 Human SwissProt: O76062 Human SwissProt: Q71KT5 Mouse Unigene: 31130 Human Unigene: 489613 Mouse
Product Picture	Sample: Lane 1: Mouse Adrenal gland tissue lysates Lane 2: Rat Adrenal gland tissue lysates Primary: Anti-TM7SF2 (SL4221R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kDa Observed band size: 58 kDa

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