Product Name	Transaldolase 1
Chinese Name	转醛醇酶/EPS8L2抗体
Alias	Dihydroxyacetone transferase; EPS8L2; Glycerone transferase; TAL; TAL H; TALDO; TALDO1; TALDOR; TALH; Transaldolase 1; Transaldolase1; Transaldolase-1; EC 2.2.1.2; TALDO_HUMAN.
Research Area	Tumour  Cell biology  immunology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	37kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Transaldolase 1: 145-250/337
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Subunit: Homodimer. DISEASE: Transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]: Results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Note=The disease is caused by mutations affecting the gene represented in this entry. SWISS: Q9H6S3 Gene ID: 64787 Database links: Entrez Gene: 64787 Human Entrez Gene: 98845 Mouse Omim: 614988 Human SwissProt: Q9H6S3 Human SwissProt: Q99K30 Mouse Unigene: 55016 Human Unigene: 27451 Mouse Transaldolase 1称醛羧移转酶 或转二羟丙酮基酶，经研究该蛋白与多发性硬化症有关。

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