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Product Name HSD17B2 Chinese Name 羟类固醇脱氢酶17β2抗体 Alias 11β-HSD2; 17 beta HSD 2; 20 alpha HSD; 20 alpha hydroxysteroid dehydrogenase; E2DH; Microsomal 17 beta hydroxysteroid dehydrogenase; Testosterone 17 beta dehydrogenase; DHB2_HUMAN. literatures Specific References (1) | SL3856R has been referenced in 1 publications.[IF=6.107] Xiao-Hu Zhao. et al. Integrative analysis reveals marker genes for intestinal mucosa barrier repairing in clinical patients. ISCIENCE. 2023 May;:106831 WB ; Human.Research Area Tumour immunology Growth factors and hormones Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 43kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HSD17B2: 151-250/387 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail HSD17B2 belongs to the short chain dehydrogenases/reductases (SDR) family. It is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. It also has 20 alpha HSD activity and uses NADH.
Function:
Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.
Subcellular Location:
Membrane; Single-pass type II membrane protein.
Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
SWISS:
P37059
Gene ID:
3294
Database links:
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