Product Name	GREB1
Chinese Name	乳腺癌雌激素调控蛋白GREB1抗体
Alias	Gene regulated by estrogen in breast cancer protein; GREB 1; GREB-1; Protein GREB1; KIAA0575; GREB1_HUMAN.
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	216kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GREB1: 1851-1949/1949
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	GREB1 is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. GREB1 is expressed in proliferating prostate tissue & prostate cancer and is thought to act as a regulator of hormone-dependent cancer growth in breast and prostate cancers. Its promoter contains putative androgen receptor response elements. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Function: May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Tissue Specificity: Expressed in proliferating prostatic tissue and prostate cancer. Similarity: Belongs to the GREB1 family. SWISS: Q4ZG55 Gene ID: 9687 Database links: Entrez Gene: 9687 Human Entrez Gene: 268527 Mouse Omim: 611736 Human SwissProt: Q4ZG55 Human SwissProt: Q3UHK3 Mouse Unigene: 467733 Human Unigene: 428062 Mouse GREB1是雌激素受体调节通路中早起反应基因，在乳腺癌、前列腺癌及前列腺增生中发挥着重要的调节作用。
Product Picture	GREB1 Antibody (Cat. SL3854R) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GREB1 antibody detected the GREB1 protein (arrow). GREB1 Antibody (Cat. SL3854R) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the GREB1 antibody detected the GREB1 protein (arrow).

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