Product Name	TNFRSF19
Chinese Name	Tumour坏死因子配体超家族成员19抗体
Alias	TROY; TAJ alpha; TAJ; TNFRSF 19; TNFRSF19; Tnfrsf20; Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19.
Research Area	Tumour  Cell biology  immunology  Growth factors and hormones  transcriptional regulatory factor  Cell Surface Molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Guinea Pig,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	43kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TROY: 102-200/423 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	TROY is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate the JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. Subunit: Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes. Similarity: Contains 3 TNFR-Cys repeats. SWISS: Q9NS68 Gene ID: 55504 Database links: Entrez Gene: 55504 Human Entrez Gene: 29820 Mouse Omim: 606122 Human SwissProt: Q9NS68 Human SwissProt: Q9JLL3 Mouse Unigene: 149168 Human Unigene: 730848 Human Unigene: 281356 Mouse
Product Picture	Sample: Siha(Human) Cell Lysate at 30 ug Primary: Anti- TNFRSF19 (SL3852R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 43 kD

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