Product Name	TNFSF9
Chinese Name	Tumour坏死因子配体超家族成员9抗体
Alias	Tumor necrosis factor ligand superfamily member 9; CD137L; TNLG5A; 4 1BB L; 4-1BB-L; 4 1BB ligand; 4 1BBL; CD137 ligand; homolog of mouse 4 1BB L; homolog of mouse 4 1BBL; ILA ligand (TNF related); Ly63l; receptor 4 1BB ligand; Tumor necrosis factor (ligand) superfamily member 9; receptor 4-1BB ligand; tumor necrosis factor ligand 5A; TNFL9_HUMAN;
Research Area	Tumour  Cell biology  immunology  Neurobiology  Cell Surface Molecule  t-lymphocyte
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	25-27kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TNFSF9: 101-200/254 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This cytokine belongs to the tumour necrosis factor (TNF) ligand family. It is a ligand for TNFRSF9, which is a costimulatory molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process, and in the generation of cytotoxic T cells. This cytokine is also shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is found to be expressed in various carcinoma cell lines, and is thought to be involved in T cell-tumour cell interaction. Function: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Subunit: Homotrimer. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Expressed in brain, placenta, lung, skeletal muscle and kidney. Similarity: Belongs to the tumor necrosis factor family. SWISS: P41273 Gene ID: 8744 Database links: Entrez Gene: 8744 Human Omim: 606182 Human SwissProt: P41273 Human Unigene: 1524 Human
Product Picture	Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti-CD137L(SL3851R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25-27 kD Observed band size: 27 kD Independently Validated Antibody, image provided by Science Direct, badge number 029578:Formalin-fixed and paraffin embedded human liver labeled with Anti-TNFSF9/CD137L Polyclonal Antibody, Unconjugated (SL3851R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

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