Product Name	GCDFP15
Chinese Name	囊性组织液体蛋白15抗体
Alias	PIP_HUMAN; PIP; Prolactin-inducible protein; Gross cystic disease fluid protein 15 (GCDFP-15); Prolactin-induced protein; Secretory actin-binding protein (SABP); gp17; GCDFP15; GPIP4; BRST-2;
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	13.5kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GCDGP15/PIP: 51-146/146
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Enables IgG binding activity; aspartic-type endopeptidase activity; and identical protein binding activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of bitter taste; negative regulation of T cell apoptotic process; and proteolysis. Located in extracellular space and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Subunit: Monomer. Interacts with AZGP1. Subcellular Location: Secreted. Tissue Specificity: Expressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands. Similarity: Belongs to the PIP family. SWISS: P12273 Gene ID: 5304 Database links: Entrez Gene: 5304 Human Omim: 176720 Human SwissProt: P12273 Human Unigene: 99949 Human GCDFP15是一种15kDa的单链蛋白，常见于组织囊性病变的囊泡液中。GCDFP-15是一种高度特异和敏感的乳腺癌标志，可用于乳腺癌的鉴别诊断，与CK7和CK20联合使用，可以用于鉴别原发或继发乳腺外派杰氏病。
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GCDFP15) Polyclonal Antibody, Unconjugated (SL3795R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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