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Product Name Tetraspan 5 Chinese Name 四分子交联体5抗体 Alias NET 4; TSPAN 5; NET4; Tetraspan 5; Tetraspan-5; Tetraspan NET 4; Tetraspan TM4SF; Tetraspanin 5; Tetraspanin5; Tetraspan5; Tspaw5; TM4SF9; Transmembrane 4 superfamily member 8; Transmembrane 4 superfamily member 9. Research Area Tumour immunology Neurobiology Cell adhesion molecule Cell Surface Molecule Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 29kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Tetraspan 5: 65-160/268 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail TSPAN5 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).
Similarity:
Belongs to the tetraspanin (TM4SF) family.
SWISS:
P62079
Gene ID:
10098
Database links:
Entrez Gene: 10098 Human
Entrez Gene: 56224 Mouse
Omim: 613136 Human
SwissProt: P62079 Human
SwissProt: P62080 Mouse
Unigene: 118118 Human
Unigene: 31927 Mouse
Unigene: 98240 Rat
四分子交联体5又称四旋蛋白5,是四分子交联体超家族是一组以四次跨膜及两个大小不等的细胞外环状结构为主要特征的膜表面蛋白。Tspaw5超家族成员可以通过彼此间的相互联系, 该家族的许多成员对恶性Tumour的转移有重要影响,它可与许多生长促进分子和粘附分子结合,以往的研究主要集中在神经系统,它在神经系统中高表达,可以影响的神经细胞及神经胶质细胞的粘附、运动和增殖,对于神经系统的形成和功能的维持起重要作用。
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