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Rabbit Anti-DDAH2 antibody
Rabbit Anti-DDAH2 antibody
DDAH; DDAHII; DDAH II; Dimethylargininase 2; DDAH2_HUMAN; AH2; DDAH 2; DDAH-2; Dimethylarginine Dimethylaminohydrolase 2; Dimethylaminohydrolase II; N(G),N(G)-dimethylarginine dimethylaminohydrolase 2; NG dimethylarginine dimethylamino hydrolase homolog;
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  • NO.:SL2785R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name DDAH2
Chinese Name 双甲基精氨酸水解酶2抗体
Alias DDAH; DDAHII; DDAH II; Dimethylargininase 2; DDAH2_HUMAN; AH2; DDAH 2; DDAH-2; Dimethylarginine Dimethylaminohydrolase 2; Dimethylaminohydrolase II; N(G),N(G)-dimethylarginine dimethylaminohydrolase 2; NG dimethylarginine dimethylamino hydrolase homolog; G6a; NG30; Protein G6a; S phase protein.  
Research Area Tumour  Cardiovascular  Cell biology  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
Clone NO. H9G41
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 30kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human DDAH2: 41-140/285 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008]

Function:
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

Tissue Specificity:
Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain.

Similarity:
Belongs to the DDAH family.

SWISS:
O95865

Gene ID:
23564

Database links:

Entrez Gene: 23564 Human

Entrez Gene: 51793 Mouse

Entrez Gene: 294239 Rat

Omim: 604744 Human

SwissProt: O95865 Human

SwissProt: Q99LD8 Mouse

SwissProt: Q6MG60 Rat

Unigene: 247362 Human

Unigene: 1457 Mouse

Unigene: 203056 Rat



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