Product Name	TREML1
Chinese Name	髓系细胞触发受体样转录因子1抗体
Alias	dJ238O23.3; GLTL1825; MGC119173; PRO3438; TLT 1; TLT1; TREM like transcript 1; Trem like transcript 1 protein; TREML 1; Triggering receptor expressed on myeloid cells like 1; Triggering receptor expressed on myeloid cells like protein 1.
Research Area	immunology  lymphocyte  t-lymphocyte  b-lymphocyte
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	33kDa
Cellular localization	cytoplasmic The cell membrane Extracellular matrix
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TREML1: 201-311/311 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012] Subunit: When phosphorylated, interacts with PTPN6. When phosphorylated, interacts with PTPN11. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. Tissue Specificity: Detected in platelets, monocytic leukemia and in T-cell leukemia. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q86YW5 Gene ID: 340205 Database links: Entrez Gene: 340205 Human Omim: 609714 Human SwissProt: Q86YW5 Human Unigene: 117331 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (mouse lymphoid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TREML1) Polyclonal Antibody, Unconjugated (SL2724R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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