Product Name	LTB4-R2
Chinese Name	白三烯B4受体2抗体
Alias	BLT2R; JULF2; Leukotriene B4 receptor 2; Leukotriene B4 receptor BLT2; LT4R2_HUMAN; LTB4 receptor JULF2; LTB4-R 2; LTB4-R2; LTB4R2; Seven transmembrane receptor BLTR2.
literatures	Specific References  (2)     |     SL2655R has been referenced in 2 publications. [IF=4.57] Zinn, Sebastian, et al. "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." Journal of Biological Chemistry (2017): jbc-M116.  IHC-F ;  Mouse.   PubMed:28242764 [IF=0] Wculek, S. Pre-metastatic neutrophils directly support highly tumourigenic breast cancer cells during lung metastasis via a leukotriene-ERK1/2 axis. Diss. UCL (University College London), 2016.  FCM ;  Mouse.   PubMed:Diss.UCL(UniversityCollegeLondon),2016.
Research Area	Tumour  Cardiovascular  immunology  Signal transduction  Lipoprotein  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Guinea Pig, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LTB4-R2: 25-120/389 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Function: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q9NPC1 Gene ID: 56413 Database links: Entrez Gene: 56413 Human Entrez Gene: 57260 Mouse Omim: 605773 Human SwissProt: Q9NPC1 Human SwissProt: Q9JJL9 Mouse Unigene: 642693 Human Unigene: 657595 Human Unigene: 159670 Mouse Unigene: 485286 Mouse 白三烯B4受体2是白三烯B4受体的新亚型，在炎症、免疫系统疾病和变态反应、包括一些Tumour中发挥着重要作用。
Product Picture	Sample: Lane 1: Human U937 cell lysates Lane 2: Human MCF-7 cell lysates Primary: Anti-LTB4-R2 (SL2655R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 41 kDa

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